Pregabalin 300 mg in Spine Surgery: Preemptive Analgesia Protocols.

Pregabalin 300 mg is increasingly used in preemptive analgesia protocols for spine surgery to reduce postoperative pain, opioid needs, and anxiety. When given 1–2 hours before surgery, Pregabalin helps minimize central sensitization, leading to smoother recovery and improved patient comfort. It is especially beneficial for patients at higher risk of chronic neuropathic pain after spinal procedures. However, dosing must be individualized to avoid dizziness or sedation, particularly in older or sensitive patients.

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